Sequence Detail

ID/Version

Q924A4 (UniProt | EBI)

Last sequence update: 2001-12-01
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Urocortin-3 {ECO:0000303|PubMed:17360501};AltName: Full=Urocortin III {ECO:0000303|PubMed:11416224}; Short=Ucn III;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 164 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ucn3	urocortin 3	44	100	3	8

Sequence references in MGI

J:70028 Lewis K, et al., Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7570-5
J:119417 Li C, et al., Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4206-11
J:160324 Kuperman Y, et al., Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8393-8
J:166245 Neufeld-Cohen A, et al., A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19020-5
J:349532 Autry AE, et al., Urocortin-3 neurons in the mouse perifornical area promote infant-directed neglect and aggression. Elife. 2021 Aug 23;10