Sequence Detail

ID/Version

Q91XQ0 O08830 E9Q010 Q91XP8 Q3V0D2 Q99MH8 Q91XP9 Q91V63 Q9QY72 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Dynein axonemal heavy chain 8;AltName: Full=Axonemal beta dynein heavy chain 8;AltName: Full=Ciliary dynein heavy chain 8;

Provider

SWISS-PROT

Sequence

Polypeptide 4731 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dnah8	dynein, axonemal, heavy chain 8	18	98	2	13

Sequence references in MGI

J:43700 Neesen J, et al., Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. Gene. 1997 Oct 24;200(1-2):193-202
J:59251 Fossella J, et al., An axonemal dynein at the Hybrid Sterility 6 locus: implications for t haplotype-specific male sterility and the evolution of species barriers [published erratum appears in Mamm Genome 2000 Mar;11(3):250]. Mamm Genome. 2000 Jan;11(1):8-15
J:79258 Samant SA, et al., The T complex distorter 2 candidate gene, Dnahc8, encodes at least two testis-specific axonemal dynein heavy chains that differ extensively at their amino and carboxyl termini. Dev Biol. 2002 Oct 1;250(1):24-43
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101666 Samant SA, et al., The mouse t complex distorter/sterility candidate, Dnahc8, expresses a gamma-type axonemal dynein heavy chain isoform confined to the principal piece of the sperm tail. Dev Biol. 2005 Sep 1;285(1):57-69
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:297137 Liu C, et al., Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility. Am J Hum Genet. 2020 Aug 6;107(2):330-341