Sequence Detail

ID/Version

Q91WC9 Q8BV05 Q8BU97 Q8BU39 (UniProt | EBI)

Last sequence update: 2004-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Diacylglycerol lipase-beta {ECO:0000303|PubMed:31991095}; Short=DAGL-beta {ECO:0000303|PubMed:31991095}; Short=DAGLbeta {ECO:0000303|PubMed:20147530, ECO:0000303|PubMed:23103940}; Short=DGL-beta {ECO:0000303|PubMed:20

Provider

SWISS-PROT

Sequence

Polypeptide 669 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Daglb	diacylglycerol lipase, beta	27	98	3	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:157850 Gao Y, et al., Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. J Neurosci. 2010 Feb 10;30(6):2017-24
J:167891 Tanimura A, et al., The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. Neuron. 2010 Feb 11;65(3):320-7
J:229982 Viader A, et al., A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation. Elife. 2016;5:e12345
J:287034 Hsu KL, et al., DAGLbeta inhibition perturbs a lipid network involved in macrophage inflammatory responses. Nat Chem Biol. 2012 Dec;8(12):999-1007
J:287132 Shin M, et al., DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages. Cell Chem Biol. 2020 Mar 19;27(3):314-321.e5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89