Sequence Detail

ID/Version

Q8VEI3 Q8VBX7 B1AV95 Q8VI77 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Hyaluronidase-3; Short=Hyal-3; EC=3.2.1.35;AltName: Full=Hyaluronoglucosaminidase-3;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 412 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hyal3	hyaluronoglucosaminidase 3	38	100	3	8

Sequence references in MGI

J:77258 Shuttleworth TL, et al., Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3. J Biol Chem. 2002 Jun 21;277(25):23008-18
J:144606 Atmuri V, et al., Hyaluronidase 3 (HYAL3) knockout mice do not display evidence of hyaluronan accumulation. Matrix Biol. 2008 Oct;27(8):653-60
J:164703 Reese KL, et al., Acidic hyaluronidase activity is present in mouse sperm and is reduced in the absence of SPAM1: evidence for a role for hyaluronidase 3 in mouse and human sperm. Mol Reprod Dev. 2010 Sep;77(9):759-72
J:248453 Orimoto AM, et al., Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia. Endocrinology. 2008 Nov;149(11):5835-47
J:248458 Hemming R, et al., Mouse Hyal3 encodes a 45- to 56-kDa glycoprotein whose overexpression increases hyaluronidase 1 activity in cultured cells. Glycobiology. 2008 Apr;18(4):280-9