Sequence Detail

ID/Version

Q8R0K2 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase TRIM31 {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:27992402};AltName: Full=Tripartite motif-containing protein 31 {ECO:0000303|PubMed:19665990};

Provider

SWISS-PROT

Sequence

Polypeptide 507 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trim31	tripartite motif-containing 31	31	98	8	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:243237 Song H, et al., The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3. Nat Commun. 2016 Dec 08;7:13727
J:275178 Liu B, et al., The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination. Nat Immunol. 2017 Feb;18(2):214-224