Sequence Detail

ID/Version

Q8R0I0 Q99N71 Q99N70 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 {ECO:0000250|UniProtKB:Q9BYF1};AltName: Full=ACE-related carboxypeptidase; EC=3.4.17.- {ECO:0000250|UniProtKB:Q9BYF1};Contains: RecName: Full=Processed angiotensin-converting enz

Provider

SWISS-PROT

Sequence

Polypeptide 805 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ace2	angiotensin converting enzyme 2	58	151	3	57

Sequence references in MGI

J:77232 Crackower MA, et al., Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002 Jun 20;417(6891):822-8
J:79044 Komatsu T, et al., Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2). DNA Seq. 2002 Aug;13(4):217-20
J:100334 Imai Y, et al., Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature. 2005 Jul 7;436(7047):112-6
J:128793 Donoghue M, et al., Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J Mol Cell Cardiol. 2003 Sep;35(9):1043-53
J:146850 Camargo SM, et al., Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology. 2009 Mar;136(3):872-82
J:187519 Fairweather SJ, et al., Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. Biochem J. 2012 Aug 15;446(1):135-48
J:213091 Xiao L, et al., Angiotensin II regulates ACE and ACE2 in neurons through p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 signaling. Am J Physiol Cell Physiol. 2013 Jun 1;304(11):C1073-9
J:259115 Kowalczuk S, et al., A protein complex in the brush-border membrane explains a Hartnup disorder allele. FASEB J. 2008 Aug;22(8):2880-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89