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Sequence Detail
ID/Version
Q8R010 Q8R2Y6 E9QP67 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Aminoacyl tRNA synthase complex-interacting multifunctional protein 2;AltName: Full=Multisynthase complex auxiliary component p38 {ECO:0000303|PubMed:12060739};AltName: Full=Protein JTV-1;
Provider SWISS-PROT
Sequence
Polypeptide 320 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 19 97 3 24
Sequence references in MGI J:84078 Kim MJ, et al., Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation. Nat Genet. 2003 Jul;34(3):330-6
J:93041 Kim JY, et al., p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7912-6
J:123455 Ko HS, et al., Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death. J Neurosci. 2005 Aug 31;25(35):7968-78
J:248554 Han JM, et al., AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11206-11
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory