Sequence Detail

ID/Version

Q8K448 Q3UUB4 Q6ZPG4 Q8BM46 Q3TE17 Q810C7 Q6P1Y0 Q8BXG7 (UniProt | EBI)

Last sequence update: 2006-10-03
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Cholesterol transporter ABCA5 {ECO:0000305}; EC=7.6.2.- {ECO:0000305|PubMed:25125465, ECO:0000305|PubMed:32687853};AltName: Full=ATP-binding cassette sub-family A member 5 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 1642 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abca5	ATP-binding cassette, sub-family A member 5	26	98	3	5

Sequence references in MGI

J:81453 Annilo T, et al., Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes. Mamm Genome. 2003 Jan;14(1):7-20
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99152 Kubo Y, et al., ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms. (Correction: v.25(13):5786). Mol Cell Biol. 2005 May;25(10):4138-49
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:160341 Ye D, et al., Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice. Biochem Biophys Res Commun. 2010 May 7;395(3):387-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302471 Ray AG, et al., Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia. J Mol Biol. 2020 Aug 7;432(17):4922-4941