Sequence Detail

ID/Version

Q8K2B0 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653};AltName: Full=Leprecan-like protein 4;AltName: Full=Prolyl 3-hydroxylase family member 4 {ECO:0000312|MGI:MGI:1913430};AltName: Full=Synaptonemal complex protein SC65 {ECO:0000

Provider

SWISS-PROT

Sequence

Polypeptide 443 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	P3h4	prolyl 3-hydroxylase family member 4 (non-enzymatic)	16	101	3	11

Sequence references in MGI

J:232567 Heard ME, et al., Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation. PLoS Genet. 2016 Apr;12(4):e1006002
J:240600 Hudson DM, et al., P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and Cross-linking Abnormality of Ehlers-Danlos Syndrome Type VIA. J Biol Chem. 2017 Mar 03;292(9):3877-3887
J:241120 Gruenwald K, et al., Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis. J Bone Miner Res. 2014 Mar;29(3):666-75