Sequence Detail

ID/Version

Q8JZL2 Q8K3M8 Q3UY93 (UniProt | EBI)

Last sequence update: 2017-11-22
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Melanin-concentrating hormone receptor 1 {ECO:0000305}; Short=MCH receptor 1; Short=MCH-R1; Short=MCHR-1;AltName: Full=G protein-coupled receptor 24;AltName: Full=MCH-1R; Short=MCH1R; Short=MCHR;AltNam

Provider

SWISS-PROT

Sequence

Polypeptide 353 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mchr1	melanin-concentrating hormone receptor 1	43	99	4	24

Sequence references in MGI

J:67355 Kokkotou EG, et al., Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain. Endocrinology. 2001 Feb;142(2):680-6
J:70827 Ehringer MA, et al., High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mamm Genome. 2001 Aug;12(8):657-63
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106819 Chen Y, et al., Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology. 2002 Jul;143(7):2469-77
J:133199 Adamantidis A, et al., Sleep architecture of the melanin-concentrating hormone receptor 1-knockout mice. Eur J Neurosci. 2008 Apr;27(7):1793-800
J:136869 Roy M, et al., Genetic inactivation of melanin-concentrating hormone receptor subtype 1 (MCHR1) in mice exerts anxiolytic-like behavioral effects. Neuropsychopharmacology. 2006 Jan;31(1):112-20