Sequence Detail

ID/Version

Q8JZL1 Q8K447 B2RRY7 Q8R5J8 (UniProt | EBI)

Last sequence update: 2002-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Interleukin-17 receptor D; Short=IL-17 receptor D; Short=IL-17RD;AltName: Full=Interleukin-17 receptor-like protein;AltName: Full=Sef homolog; Short=mSef;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 738 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il17rd	interleukin 17 receptor D	9	108	3	86

Sequence references in MGI

J:76546 Lin W, et al., Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Mech Dev. 2002 May;113(2):163-8
J:82957 Kovalenko D, et al., Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation. J Biol Chem. 2003 Apr 18;278(16):14087-91
J:87285 Xiong S, et al., hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling. J Biol Chem. 2003 Dec 12;278(50):50273-82
J:203635 Miraoui H, et al., Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. Am J Hum Genet. 2013 May 2;92(5):725-43
J:287032 Zhao G, et al., Negative regulation of TGFbeta-induced lens epithelial to mesenchymal transition (EMT) by RTK antagonists. Exp Eye Res. 2015 Mar;132:9-16