Sequence Detail

ID/Version

Q8CIT0 Q14AA2 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Corticotropin-releasing hormone {ECO:0000303|PubMed:19912808};AltName: Full=Corticoliberin;AltName: Full=Corticotropin-releasing factor; Short=CRF;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 187 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Crh	corticotropin releasing hormone	126	116	3	30

Sequence references in MGI

J:23082 Muglia L, et al., Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature. 1995 Feb 2;373(6513):427-32
J:189229 Lemos JC, et al., Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. Nature. 2012 Oct 18;490(7420):402-6
J:236525 Li K, et al., A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors. Cell. 2016 Sep 22;167(1):60-72.e11
J:340714 de Leon Reyes NS, et al., Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice. Cell. 2023 Sep 14;186(19):4152-4171.e31
J:383027 Donelan J, et al., Corticotropin-releasing hormone induces skin vascular permeability through a neurotensin-dependent process. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7759-64