Sequence Detail

ID/Version

Q8CG72 Q80UW9 A3KFY3 Q921U6 Q8R575 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=ADP-ribosylhydrolase ARH3;AltName: Full=ADP-ribose glycohydrolase ARH3 {ECO:0000305};AltName: Full=ADP-ribosylhydrolase 3 {ECO:0000303|PubMed:24191052};AltName: Full=O-acetyl-ADP-ribose deacetylase ARH3 {ECO:0000305}; EC=3.5.1.- {ECO

Provider

SWISS-PROT

Sequence

Polypeptide 370 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adprs	ADP-ribosylserine hydrolase	31	96	3	10

Sequence references in MGI

J:83667 Glowacki G, et al., The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse. Protein Sci. 2002 Jul;11(7):1657-70
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:202975 Mashimo M, et al., ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18964-9
J:291285 Mashimo M, et al., PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells. JCI Insight. 2019 Feb 21;4(4)
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89