Sequence Detail

ID/Version

Q8CCN1 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=NACHT, LRR and PYD domains-containing protein 10;

Provider

SWISS-PROT

Sequence

Polypeptide 673 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nlrp10	NLR family, pyrin domain containing 10	35	97	3	8

Sequence references in MGI

J:90680 Wang Y, et al., PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1. Int Immunol. 2004 Jun;16(6):777-86
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161002 Imamura R, et al., Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J Immunol. 2010 May 15;184(10):5874-84
J:183989 Eisenbarth SC, et al., NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. Nature. 2012 Apr 26;484(7395):510-3
J:190699 Joly S, et al., Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans. J Immunol. 2012 Nov 15;189(10):4713-7
J:245258 Damm A, et al., Epidermal NLRP10 contributes to contact hypersensitivity responses in mice. Eur J Immunol. 2016 Aug;46(8):1959-69