Sequence Detail

ID/Version

Q8CCI5 Q9WVK2 B2RRB6 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=RING1 and YY1-binding protein;AltName: Full=Death effector domain-associated factor; Short=DED-associated factor;

Provider

SWISS-PROT

Sequence

Polypeptide 228 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rybp	RING1 and YY1 binding protein	24	107	4	56

Sequence references in MGI

J:65786 Garcia E, et al., RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1. EMBO J. 1999 Jun 15;18(12):3404-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117714 Arrigoni R, et al., The Polycomb-associated protein Rybp is a ubiquitin binding protein. FEBS Lett. 2006 Nov 13;580(26):6233-41
J:134591 Pirity MK, et al., Rybp/DEDAF is required for early postimplantation and for central nervous system development. Mol Cell Biol. 2005 Aug;25(16):7193-202
J:172960 Neira JL, et al., The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA. Biochemistry. 2009 Feb 17;48(6):1348-60
J:186106 Tavares L, et al., RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell. 2012 Feb 17;148(4):664-78
J:243420 Almeida M, et al., PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science. 2017 Jun 09;356(6342):1081-1084
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89