Sequence Detail

ID/Version

Q8C9J3 E0CYG3 G0Z098 A2RSG5 (UniProt | EBI)

Last sequence update: 2018-10-10
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Sperm flagellar protein 2;AltName: Full=Protein KPL2;

Provider

SWISS-PROT

Sequence

Polypeptide 1724 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spef2	sperm flagellar 2	46	96	3	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:159553 Sironen A, et al., Expression of SPEF2 during mouse spermatogenesis and identification of IFT20 as an interacting protein. Biol Reprod. 2010 Mar;82(3):580-90
J:176695 Sironen A, et al., Loss of SPEF2 Function in Mice Results in Spermatogenesis Defects and Primary Ciliary Dyskinesia. Biol Reprod. 2011 Oct;85(4):690-701
J:242894 Lehti MS, et al., SPEF2 functions in microtubule-mediated transport in elongating spermatids to ensure proper male germ cell differentiation. Development. 2017 Jul 15;144(14):2683-2693
J:264497 Lehti MS, et al., Cilia-related protein SPEF2 regulates osteoblast differentiation. Sci Rep. 2018 Jan 16;8(1):859