Sequence Detail

ID/Version

Q8BFQ3 Q80T34 Q3U1L3 Q148P7 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=G-protein coupled receptor 68;AltName: Full=Ovarian cancer G-protein coupled receptor 1 homolog {ECO:0000303|PubMed:17728215};

Provider

SWISS-PROT

Sequence

Polypeptide 365 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpr68	G protein-coupled receptor 68	36	99	2	14

Sequence references in MGI

J:83410 Vassilatis DK, et al., The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4903-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:149315 Li H, et al., Abnormalities in osteoclastogenesis and decreased tumorigenesis in mice deficient for ovarian cancer G protein-coupled receptor 1. PLoS One. 2009;4(5):e5705
J:226642 Wei WC, et al., Reciprocal regulation of two G protein-coupled receptors sensing extracellular concentrations of Ca2+ and H. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10738-43
J:257895 Huang XP, et al., Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature. 2015 Nov 26;527(7579):477-83
J:261127 Xu J, et al., GPR68 Senses Flow and Is Essential for Vascular Physiology. Cell. 2018 Apr 19;173(3):762-775.e16