Sequence Detail

ID/Version

Q811D0 Q6PGB5 Q8CGN7 Q62402 (UniProt | EBI)

Last sequence update: 2003-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Disks large homolog 1 {ECO:0000305};AltName: Full=Embryo-dlg/synapse-associated protein 97; Short=E-dlg/SAP97;AltName: Full=Synapse-associated protein 97; Short=SAP-97; Short=SAP97;

Provider

SWISS-PROT

Sequence

Polypeptide 905 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dlg1	discs large MAGUK scaffold protein 1	193	115	4	36

Sequence references in MGI

J:44891 Lin L, et al., Identification of the mouse homologue of human discs large and rat SAP97 genes. Biochim Biophys Acta. 1997 Nov 28;1362(1):1-5
J:67360 Caruana G, et al., Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene. Mol Cell Biol. 2001 Mar;21(5):1475-83
J:95586 Folco EJ, et al., Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5. Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H681-90
J:201438 Marcello E, et al., Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. J Clin Invest. 2013 Jun 3;123(6):2523-38
J:222817 Posokhova E, et al., GPR124 functions as a WNT7-specific coactivator of canonical beta-catenin signaling. Cell Rep. 2015 Jan 13;10(2):123-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:333121 Becamel C, et al., The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J Biol Chem. 2004 May 7;279(19):20257-66
J:333179 Kantardzhieva A, et al., MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane. FEBS J. 2006 Mar;273(6):1152-65