Sequence Detail

ID/Version

Q7TNJ0 Q9D619 Q6R315 Q7TNI9 B2RT61 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Dendritic cell-specific transmembrane protein; Short=DC-STAMP; Short=mDC-STAMP;AltName: Full=Dendrocyte-expressed seven transmembrane protein;AltName: Full=Transmembrane 7 superfamily member 4;

Provider

SWISS-PROT

Sequence

Polypeptide 470 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dcstamp	dendrocyte expressed seven transmembrane protein	28	96	2	8

Sequence references in MGI

J:93945 Kukita T, et al., RANKL-induced DC-STAMP is essential for osteoclastogenesis. J Exp Med. 2004 Oct 4;200(7):941-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100555 Yagi M, et al., DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med. 2005 Aug 1;202(3):345-51
J:140227 Sawatani Y, et al., The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function. Int Immunol. 2008 Oct;20(10):1259-68
J:183967 Eleveld-Trancikova D, et al., The DC-derived protein DC-STAMP influences differentiation of myeloid cells. Leukemia. 2008 Feb;22(2):455-9
J:184052 Eleveld-Trancikova D, et al., The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum. J Leukoc Biol. 2005 Mar;77(3):337-43
J:184740 Miyamoto T, The dendritic cell-specific transmembrane protein DC-STAMP is essential for osteoclast fusion and osteoclast bone-resorbing activity. Mod Rheumatol. 2006;16(6):341-2
J:184741 Yagi M, et al., Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells. J Bone Miner Metab. 2006;24(5):355-8
J:244641 Miyamoto H, et al., Osteoclast stimulatory transmembrane protein and dendritic cell-specific transmembrane protein cooperatively modulate cell-cell fusion to form osteoclasts and foreign body giant cells. J Bone Miner Res. 2012 Jun;27(6):1289-97