Sequence Detail

ID/Version

Q7TN08 Q6PDF4 Q8BHZ7 (UniProt | EBI)

Last sequence update: 2008-03-18
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Dapper homolog 2; Short=mDpr2;AltName: Full=Dapper antagonist of catenin 2;

Provider

SWISS-PROT

Sequence

Polypeptide 757 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dact2	dishevelled-binding antagonist of beta-catenin 2	17	111	3	12

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111589 Fisher DA, et al., Three Dact gene family members are expressed during embryonic development and in the adult brains of mice. Dev Dyn. 2006 Jul 31;235(9):2620-2630
J:139684 Meng F, et al., Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGF{beta} signaling. J Cell Sci. 2008 Sep 1;121(Pt 17):2904-12
J:164447 Lee WC, et al., Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells. Am J Physiol Renal Physiol. 2010 Oct;299(4):F740-51
J:187547 Kivimae S, et al., All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. BMC Biochem. 2011;12:33
J:187575 Su Y, et al., The evolutionally conserved activity of Dapper2 in antagonizing TGF-beta signaling. FASEB J. 2007 Mar;21(3):682-90