Sequence Detail

ID/Version

Q7M750 Q6P903 (UniProt | EBI)

Last sequence update: 2003-12-15
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Opalin {ECO:0000303|PubMed:17442045};AltName: Full=Oligodendrocytic myelin paranodal and inner loop protein;AltName: Full=Transmembrane protein 10 {ECO:0000303|PubMed:18439243};

Provider

SWISS-PROT

Sequence

Polypeptide 143 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Opalin	oligodendrocytic myelin paranodal and inner loop protein	7	106	2	3

Sequence references in MGI

J:74484 Nobile C, et al., Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia. Gene. 2002 Jan 9;282(1-2):87-94
J:129500 Aruga J, et al., An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin. J Neurochem. 2007 Sep;102(5):1533-47
J:137506 Yoshikawa F, et al., Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane. J Biol Chem. 2008 Jul 25;283(30):20830-40
J:257142 Yoshikawa F, et al., Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments. PLoS One. 2016;11(11):e0166732
J:283177 de Faria O Jr, et al., TMEM10 Promotes Oligodendrocyte Differentiation and is Expressed by Oligodendrocytes in Human Remyelinating Multiple Sclerosis Plaques. Sci Rep. 2019 Mar 5;9(1):3606
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89