Sequence Detail

ID/Version

Q6SJE0 Q6SJD9 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=GDNF family receptor alpha-like;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 393 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gfral	GDNF family receptor alpha like	38	96	3	18

Sequence references in MGI

J:251850 Emmerson PJ, et al., The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL. Nat Med. 2017 Oct;23(10):1215-1219
J:251855 Mullican SE, et al., GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. Nat Med. 2017 Oct;23(10):1150-1157
J:251981 Yang L, et al., GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nat Med. 2017 Oct;23(10):1158-1166
J:254140 Hsu JY, et al., Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature. 2017 Oct 12;550(7675):255-259