Sequence Detail

ID/Version

Q6PEE3 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Ribonucleoside-diphosphate reductase subunit M2 B; EC=1.17.4.1;AltName: Full=TP53-inducible ribonucleotide reductase M2 B;AltName: Full=p53-inducible ribonucleotide reductase small subunit 2-like protein; Short=p53R2;

Provider

SWISS-PROT

Sequence

Polypeptide 351 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	35	97	3	14

Sequence references in MGI

J:72397 Guittet O, et al., Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. J Biol Chem. 2001 Nov 2;276(44):40647-51
J:84841 Kimura T, et al., Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools. Nat Genet. 2003 Aug;34(4):440-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89