Sequence Detail

ID/Version

Q6PAC3 E9QPL0 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=DDB1- and CUL4-associated factor 13;AltName: Full=WD repeat and SOF domain-containing protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 445 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dcaf13	DDB1 and CUL4 associated factor 13	32	100	3	15

Sequence references in MGI

J:266543 Zhang YL, et al., DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. EMBO J. 2018 Sep 14;37(18)
J:298149 Liu Y, et al., Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development. Sci Rep. 2019 Apr 18;9(1):6278
J:302674 Zhang J, et al., The CRL4-DCAF13 ubiquitin E3 ligase supports oocyte meiotic resumption by targeting PTEN degradation. Cell Mol Life Sci. 2020 Jun;77(11):2181-2197
J:302700 Zhang J, et al., Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing. Cell Death Differ. 2019 Jul;26(7):1251-1266
J:332976 Yan X, et al., DCAF13 is essential for the pathogenesis of preeclampsia through its involvement in endometrial decidualization. Mol Cell Endocrinol. 2022 Aug 4;556:111741
J:333016 Shan BQ, et al., DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting PERP expression. Cancer Sci. 2022 May;113(5):1587-1600