Sequence Detail

ID/Version

Q6IYF8 Q3UQE9 Q0VEK6 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=2-oxoglutarate receptor 1;AltName: Full=Alpha-ketoglutarate receptor 1;AltName: Full=G-protein coupled receptor 99;

Provider

SWISS-PROT

Sequence

Polypeptide 337 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Oxgr1	oxoglutarate (alpha-ketoglutarate) receptor 1	30	98	5	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:198383 Kanaoka Y, et al., Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. J Biol Chem. 2013 Apr 19;288(16):10967-72
J:201611 Tokonami N, et al., alpha-Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism. J Clin Invest. 2013 Jul 1;123(7):3166-71
J:338988 Bankova LG, et al., Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99. Proc Natl Acad Sci U S A. 2016 May 31;113(22):6242-7
J:355006 Zeng YR, et al., The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary innate immune response. J Clin Invest. 2023 Mar 15;133(6)