Sequence Detail

ID/Version

Q69ZK6 Q8C4I5 E9QMM8 Q8C5Q9 Q6NV48 Q8BUF5 G3UZM1 (UniProt | EBI)

Last sequence update: 2026-01-28
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Jumonji domain-containing protein 1C; EC=1.14.11.- {ECO:0000269|PubMed:20530532};

Provider

SWISS-PROT

Sequence

Polypeptide 2531 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Jmjd1c	jumonji domain containing 1C	21	99	4	279

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:173421 Kim SM, et al., Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance. Nucleic Acids Res. 2010 Oct 1;38(19):6389-403
J:203917 Kuroki S, et al., JMJD1C, a JmjC domain-containing protein, is required for long-term maintenance of male germ cells in mice. Biol Reprod. 2013 Oct;89(4):93
J:286716 Viscarra JA, et al., Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis. Nat Commun. 2020 Feb 7;11(1):796
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:365062 Yin Y, et al., Jmjd1c demethylates STAT3 to restrain plasma cell differentiation and rheumatoid arthritis. Nat Immunol. 2022 Sep;23(9):1342-1354