Sequence Detail

ID/Version

Q64505 Q8BFR7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Cytochrome P450 7A1 {ECO:0000250|UniProtKB:P22680};AltName: Full=24-hydroxycholesterol 7-alpha-hydroxylase {ECO:0000250|UniProtKB:P22680}; EC=1.14.14.26 {ECO:0000250|UniProtKB:P22680};AltName: Full=CYPVII;AltName: Full=Cholesterol 7-

Provider

SWISS-PROT

Sequence

Polypeptide 503 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	39	100	4	7

Sequence references in MGI

J:18307 Tzung KW, et al., Structure of the mouse cholesterol 7 alpha-hydroxylase gene. Genomics. 1994 May 1;21(1):244-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:125929 Ponugoti B, et al., Functional Interaction of Hepatic Nuclear Factor-4 and Peroxisome Proliferator-Activated Receptor-{gamma} Coactivator 1{alpha} in CYP7A1 Regulation Is Inhibited by a Key Lipogenic Activator, Sterol Regulatory Element-Binding Protein-1c. Mol Endocrinol. 2007 Nov;21(11):2698-712