Sequence Detail

ID/Version

Q63844 Q91YW5 Q8K0X5 Q61531 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Mitogen-activated protein kinase 3; Short=MAP kinase 3; Short=MAPK 3; EC=2.7.11.24;AltName: Full=ERT2;AltName: Full=Extracellular signal-regulated kinase 1; Short=ERK-1;AltName: Full=Insulin-stimulated MAP2 ki

Provider

SWISS-PROT

Sequence

Polypeptide 380 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mapk3	mitogen-activated protein kinase 3	137	235	3	19

Sequence references in MGI

J:3921 Tanner B, et al., Molecular cloning of a mouse extracellular signal regulated kinase (erk-1). Biochim Biophys Acta. 1993 Jan 23;1171(3):319-20
J:4073 Ershler M, et al., Novel CDC2-related protein kinases produced in murine hematopoietic stem cells. Gene. 1993 Feb 28;124(2):305-6
J:11434 De Miguel C, et al., Molecular analysis of microtubule-associated protein-2 kinase cDNA from mouse and rat brain. DNA Cell Biol. 1991 Sep;10(7):505-14
J:31517 Crews CM, et al., Mouse Erk-1 gene product is a serine/threonine protein kinase that has the potential to phosphorylate tyrosine. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8845-9
J:78465 Murphy LO, et al., Molecular interpretation of ERK signal duration by immediate early gene products. Nat Cell Biol. 2002 Aug;4(8):556-64
J:89950 Vomastek T, et al., Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists. Proc Natl Acad Sci U S A. 2004 May 4;101(18):6981-6
J:98544 Hsu SH, et al., bHLH-zip transcription factor Spz1 mediates mitogen-activated protein kinase cell proliferation, transformation, and tumorigenesis. Cancer Res. 2005 May 15;65(10):4041-50
J:102896 Parra JL, et al., Features of the catalytic domains and C termini of the MAPK signal-integrating kinases Mnk1 and Mnk2 determine their differing activities and regulatory properties. J Biol Chem. 2005 Nov 11;280(45):37623-33
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:180564 Yao Z, et al., The ERK signaling cascade--views from different subcellular compartments. Biofactors. 2009 Sep-Oct;35(5):407-16
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89