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Sequence Detail
ID/Version
Q62264 (UniProt | EBI) Last sequence update: 1997-11-01
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Thyroid hormone-inducible hepatic protein;AltName: Full=Spot 14 protein; Short=S14; Short=SPOT14;
Provider SWISS-PROT
Sequence
Polypeptide 150 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Thrsp thyroid hormone responsive 16 105 3 47
Sequence references in MGI J:37871 Grillasca JP, et al., Cloning and initial characterization of human and mouse Spot 14 genes. FEBS Lett. 1997 Jan 13;401(1):38-42
J:71785 Zhu Q, et al., Spot 14 Gene Deletion Increases Hepatic de Novo Lipogenesis. Endocrinology. 2001 Oct;142(10):4363-70
J:129452 Zhu Q, et al., The Spot 14 protein is required for de novo lipid synthesis in the lactating mammary gland. Endocrinology. 2005 Aug;146(8):3343-50
J:166241 Colbert CL, et al., Crystal structure of Spot 14, a modulator of fatty acid synthesis. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18820-5
J:244299 Anderson GW, et al., The Thrsp null mouse (Thrsp(tm1cnm)) and diet-induced obesity. Mol Cell Endocrinol. 2009 Apr 10;302(1):99-107
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory