Sequence Detail

ID/Version

Q61831 Q9R0U6 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Mitogen-activated protein kinase 10; Short=MAP kinase 10; Short=MAPK 10; EC=2.7.11.24;AltName: Full=MAP kinase p49 3F12;AltName: Full=Stress-activated protein kinase JNK3;AltName: Full=c-Jun N-terminal kinase 3;

Provider

SWISS-PROT

Sequence

Polypeptide 464 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mapk10	mitogen-activated protein kinase 10	33	110	3	14

Sequence references in MGI

J:31286 Martin JH, et al., Developmental expression in the mouse nervous system of the p493F12 SAP kinase. Brain Res Mol Brain Res. 1996 Jan;35(1-2):47-57
J:43658 Yang DD, et al., Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature. 1997 Oct 23;389(6653):865-70
J:57455 Koyano S, et al., A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1. FEBS Lett. 1999 Sep 3;457(3):385-8
J:64817 Ito M, et al., JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol Cell Biol. 1999 Nov;19(11):7539-48
J:126083 Kim Y, et al., MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J Exp Med. 2007 Sep 3;204(9):2063-74
J:186089 Yoshitane H, et al., JNK regulates the photic response of the mammalian circadian clock. EMBO Rep. 2012 May;13(5):455-61
J:220433 Atkinson PJ, et al., Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons. Hear Res. 2011 Aug;278(1-2):77-85
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89