Sequence Detail

ID/Version

Q61768 Q5BL10 Q61580 O08711 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Kinesin-1 heavy chain;AltName: Full=Conventional kinesin heavy chain;AltName: Full=Ubiquitous kinesin heavy chain; Short=UKHC;

Provider

SWISS-PROT

Sequence

Polypeptide 963 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kif5b	kinesin family member 5B	83	100	4	31

Sequence references in MGI

J:39759 Meng YX, et al., Suppression of the expression of a pancreatic beta-cell form of the kinesin heavy chain by antisense oligonucleotides inhibits insulin secretion from primary cultures of mouse beta-cells. Endocrinology. 1997 May;138(5):1979-87
J:43245 Gudkov AV, et al., Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3744-8
J:48447 Tanaka Y, et al., Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell. 1998 Jun 26;93(7):1147-58
J:123202 Vidal RL, et al., Marlin-1 and conventional kinesin link GABA(B) receptors to the cytoskeleton and regulate receptor transport. Mol Cell Neurosci. 2007 Jul;35(3):501-12
J:178439 Wang R, et al., TLRR (lrrc67) interacts with PP1 and is associated with a cytoskeletal complex in the testis. Biol Cell. 2010 Mar;102(3):173-89
J:235257 Matsuzaki F, et al., Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation. Mol Biol Cell. 2011 Dec;22(23):4602-20
J:238467 Setou M, et al., Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature. 2002 May 02;417(6884):83-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87