Sequence Detail

ID/Version

Q61495 A8WFQ4 Q8CE03 (UniProt | EBI)

Last sequence update: 2005-03-01
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Desmoglein-1-alpha; Short=Desmoglein-1; Short=Dsg1-alpha;AltName: Full=DG1;AltName: Full=DGI;AltName: Full=Desmosomal glycoprotein I;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1057 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dsg1a	desmoglein 1 alpha	44	113	4	4

Sequence references in MGI

J:18927 Buxton RS, et al., Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18. Genomics. 1994 Jun;21(3):510-6
J:77474 Hanakawa Y, et al., Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. J Clin Invest. 2002 Jul;110(1):53-60
J:84153 Pulkkinen L, et al., Novel member of the mouse desmoglein gene family: Dsg1-beta. Exp Dermatol. 2003 Feb;12(1):11-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:295138 Kugelmann D, et al., Desmoglein 1 Deficiency Causes Lethal Skin Blistering. J Invest Dermatol. 2019 Jul;139(7):1596-1599.e2
J:383052 Sherrill JD, et al., Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis. Mucosal Immunol. 2014 May;7(3):718-29