Sequence Detail

ID/Version

Q61409 Q8CIX5 Q9Z1J9 (UniProt | EBI)

Last sequence update: 2007-01-09
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B {ECO:0000305|PubMed:10454575}; EC=3.1.4.17 {ECO:0000269|PubMed:10454575};AltName: Full=CGIPDE1;AltName: Full=Cyclic GMP-inhibited phosphodiesterase B; Short=CGI-PDE B;

Provider

SWISS-PROT

Sequence

Polypeptide 1100 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pde3b	phosphodiesterase 3B, cGMP-inhibited	31	100	3	8

Sequence references in MGI

J:36022 Lobbert RW, et al., Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1. Genomics. 1996 Oct 15;37(2):211-8
J:91945 Patrucco E, et al., PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell. 2004 Aug 6;118(3):375-87
J:116435 Liu H, et al., Importance of cAMP-response element-binding protein in regulation of expression of the murine cyclic nucleotide phosphodiesterase 3B (Pde3b) gene in differentiating 3T3-L1 preadipocytes. J Biol Chem. 2006 Jul 28;281(30):21096-113
J:135467 Kitamura T, et al., Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt. Mol Cell Biol. 1999 Sep;19(9):6286-96
J:270787 Xia W, et al., Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance. Cell Rep. 2018 May 15;23(7):1948-1961
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89