Sequence Detail

ID/Version

Q61271 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Activin receptor type-1B; EC=2.7.11.30;AltName: Full=Activin receptor type IB; Short=ACTR-IB;AltName: Full=Activin receptor-like kinase 4; Short=ALK-4;AltName: Full=Serine/threonine-protein kinase receptor R2;

Provider

SWISS-PROT

Sequence

Polypeptide 505 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acvr1b	activin A receptor, type 1B	70	112	4	28

Sequence references in MGI

J:27756 Verschueren K, et al., Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis. Mech Dev. 1995 Jul;52(1):109-23
J:60559 Shoji H, et al., Identification and characterization of a PDZ protein that interacts with activin type II receptors. J Biol Chem. 2000 Feb 25;275(8):5485-92
J:116938 Muller MR, et al., Transgenic mice expressing dominant-negative activin receptor IB in forebrain neurons reveal novel functions of activin at glutamatergic synapses. J Biol Chem. 2006 Sep 29;281(39):29076-84
J:140377 Esguerra CV, et al., Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination. Development. 2007 Dec;134(24):4381-93
J:171766 Qiu W, et al., Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality. J Invest Dermatol. 2011 May;131(5):1067-76