Sequence Detail

ID/Version

Q5MJS3 Q4FJP0 Q6PKA8 Q8JZP7 Q571A3 (UniProt | EBI)

Last sequence update: 2005-02-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Extracellular serine/threonine protein kinase FAM20C {ECO:0000305}; EC=2.7.11.1 {ECO:0000269|PubMed:22900076};AltName: Full=Dentin matrix protein 4 {ECO:0000303|PubMed:17369251}; Short=DMP-4 {ECO:0000303|PubMed:17369251};AltN

Provider

SWISS-PROT

Sequence

Polypeptide 579 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fam20c	FAM20C, golgi associated secretory pathway kinase	41	101	4	6

Sequence references in MGI

J:122675 Hao J, et al., Dentin matrix protein 4, a novel secretory calcium-binding protein that modulates odontoblast differentiation. J Biol Chem. 2007 May 25;282(21):15357-65
J:186384 Vogel P, et al., Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice. Vet Pathol. 2012 Nov;49(6):998-1017
J:211241 O'Sullivan J, et al., Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome. Am J Hum Genet. 2011 May 13;88(5):616-20
J:222145 Ishikawa HO, et al., The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. PLoS One. 2012;7(8):e42988
J:222164 Cui J, et al., A secretory kinase complex regulates extracellular protein phosphorylation. Elife. 2015;4:e06120