Sequence Detail

ID/Version

Q4PLS0 A0A140LJ71 Q8C6M5 A0A140LHK4 (UniProt | EBI)

Last sequence update: 2005-07-19
Last annotation update: 2026-09-02

Sequence description from provider

RecName: Full=NACHT, LRR and PYD domains-containing protein 2 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 1046 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nlrp2	NLR family, pyrin domain containing 2	11	108	4	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:184221 Peng H, et al., Nlrp2, a maternal effect gene required for early embryonic development in the mouse. PLoS One. 2012;7(1):e30344
J:237496 Kuchmiy AA, et al., NLRP2 controls age-associated maternal fertility. J Exp Med. 2016 Dec 12;213(13):2851-2860
J:275254 Mahadevan S, et al., Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming. Sci Rep. 2017 Mar 20;7:44667