Sequence Detail

ID/Version

Q4LDD4 Q58ET6 Q6PEQ9 B2RUJ3 Q3US99 Q3UDD2 Q6ZQ48 (UniProt | EBI)

Last sequence update: 2009-03-24
Last annotation update: 2025-04-09

Sequence description from provider

RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1;AltName: Full=Centaurin-delta-2 {ECO:0000250|UniProtKB:Q96P48}; Short=Cnt-d2 {ECO:0000250|UniProtKB:Q96P48};

Provider

SWISS-PROT

Sequence

Polypeptide 1452 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arap1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	24	98	3	30

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:254915 Moshiri A, et al., Arap1 Deficiency Causes Photoreceptor Degeneration in Mice. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1709-1718
J:267854 Segeletz S, et al., ARAP1 Bridges Actin Dynamics and AP-3-Dependent Membrane Traffic in Bone-Digesting Osteoclasts. iScience. 2018 Aug 31;6:199-211
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:327297 Shao A, et al., Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death. Dis Model Mech. 2022 Jul 1;15(7):dmm049343