Sequence Detail

ID/Version

Q3UYH7 F8VPM8 (UniProt | EBI)

Last sequence update: 2012-02-22
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=G protein-coupled receptor kinase 3 {ECO:0000312|MGI:MGI:87941}; EC=2.7.11.16 {ECO:0000269|PubMed:33886552, ECO:0000269|PubMed:38883814};AltName: Full=Beta-adrenergic receptor kinase 2 {ECO:0000250|UniProtKB:P26819}; Short=Be

Provider

SWISS-PROT

Sequence

Polypeptide 688 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Grk3	G protein-coupled receptor kinase 3	50	99	2	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:341400 Arveseth CD, et al., Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. PLoS Biol. 2021 Apr;19(4):e3001191
J:349923 George K, et al., Robust GRK2/3/6-dependent desensitization of oxytocin receptor in neurons. iScience. 2024 Jun 21;27(6):110047