Sequence Detail

ID/Version

Q3UP38 B9EKF2 A0A1D5RLZ8 (UniProt | EBI)

Last sequence update: 2021-04-07
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=EF-hand calcium-binding domain-containing protein 4B;AltName: Full=Calcium release-activated channel regulator 2A;AltName: Full=Ras-related protein Rab-46 {ECO:0000250|UniProtKB:Q9BSW2}; EC=3.6.5.2 {ECO:0000250|UniProtKB:Q9BSW2};

Provider

SWISS-PROT

Sequence

Polypeptide 726 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cracr2a	calcium release activated channel regulator 2A	70	97	4	3

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:259523 Srikanth S, et al., A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals. Sci Signal. 2016 Mar 22;9(420):ra31
J:264324 Woo JS, et al., CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses. J Immunol. 2018 Aug 15;201(4):1174-1185