Sequence Detail

ID/Version

Q07104 Q3TUX1 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Growth/differentiation factor 3; Short=GDF-3;AltName: Full=VG-1-related protein 2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 366 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gdf3	growth differentiation factor 3	33	105	3	34

Sequence references in MGI

J:3327 Jones CM, et al., Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family. Mol Endocrinol. 1992 Nov;6(11):1961-8
J:3946 McPherron AC, et al., GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines. J Biol Chem. 1993 Feb 15;268(5):3444-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104371 Chen C, et al., The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo. Development. 2006 Jan;133(2):319-29
J:109875 Witthuhn BA, et al., Upregulation of bone morphogenetic protein GDF-3/Vgr-2 expression in adipose tissue of FABP4/aP2 null mice. Cytokine. 2001 May 7;14(3):129-35
J:127541 Andersson O, et al., Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development. Dev Biol. 2007 Nov 15;311(2):500-11
J:136322 Andersson O, et al., Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7252-6