Sequence Detail

ID/Version

Q01147 (UniProt | EBI)

Last sequence update: 2020-10-07
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Cyclic AMP-responsive element-binding protein 1; Short=CREB-1; Short=cAMP-responsive element-binding protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 327 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Creb1	cAMP responsive element binding protein 1	119	126	4	91

Sequence references in MGI

J:1675 Cole TJ, et al., The mouse CREB (cAMP responsive element binding protein) gene: structure, promoter analysis, and chromosomal localization. Genomics. 1992 Aug;13(4):974-82
J:50412 Ruppert S, et al., Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J. 1992 Apr;11(4):1503-12
J:75993 Gau D, et al., Phosphorylation of CREB Ser142 Regulates Light-Induced Phase Shifts of the Circadian Clock. Neuron. 2002 Apr 11;34(2):245-53
J:139576 Ananieva O, et al., The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. Nat Immunol. 2008 Sep;9(9):1028-36
J:180535 Ma X, et al., CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes. Biochem J. 2011 Oct 1;439(1):27-38
J:209480 Zhang EE, et al., Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nat Med. 2010 Oct;16(10):1152-6
J:291988 Otaka N, et al., Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury. Circ Res. 2018 Dec 7;123(12):1326-1338
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:320480 Wang L, et al., TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver. Cell Metab. 2022 Jan 4;34(1):158-170.e5