Sequence Detail

ID/Version

P97436 O09087 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Homeobox protein Nkx-3.1 {ECO:0000303|PubMed:8943214};AltName: Full=Homeobox protein NK-3 homolog A {ECO:0000250|UniProtKB:Q99801};

Provider

SWISS-PROT

Sequence

Polypeptide 237 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nkx3-1	NK3 homeobox 1	113	133	3	16

Sequence references in MGI

J:37120 Bieberich CJ, et al., Prostate-specific and androgen-dependent expression of a novel homeobox gene. J Biol Chem. 1996 Dec 13;271(50):31779-82
J:40046 Sciavolino PJ, et al., Tissue-specific expression of murine Nkx3.1 in the male urogenital system. Dev Dyn. 1997 May;209(1):127-38
J:54465 Bhatia-Gaur R, et al., Roles for Nkx3.1 in prostate development and cancer. Genes Dev. 1999 Apr 15;13(8):966-77
J:56673 Tanaka M, et al., Expression of the Nkx3.1 homobox gene during pre and postnatal development. Mech Dev. 1999 Jul;85(1-2):179-82
J:63764 Schneider A, et al., Targeted disruption of the nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate. Mech Dev. 2000 Jul;95(1-2):163-74
J:77034 Kim MJ, et al., Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res. 2002 Jun 1;62(11):2999-3004
J:114835 Ju JH, et al., Physical and functional interactions between the prostate suppressor homeoprotein NKX3.1 and serum response factor. J Mol Biol. 2006 Jul 28;360(5):989-99
J:139640 Wang X, et al., Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. Dev Dyn. 2008 Sep 24;237(10):2963-2972