Sequence Detail

ID/Version

P97401 O09093 Q91W58 O09075 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Secreted frizzled-related protein 3; Short=sFRP-3;AltName: Full=Frezzled;AltName: Full=Fritz;AltName: Full=Frizzled-related protein 1;AltName: Full=FrzB-1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 323 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Frzb	frizzled-related protein	33	134	3	11

Sequence references in MGI

J:39275 Rattner A, et al., A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2859-63
J:40600 Mayr T, et al., Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mech Dev. 1997 Apr;63(1):109-25
J:40838 Leyns L, et al., Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell. 1997 Mar 21;88(6):747-56
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:147775 Kwon HS, et al., Myocilin is a modulator of Wnt signaling. Mol Cell Biol. 2009 Apr;29(8):2139-54