Sequence Detail

ID/Version

P97299 O35297 O08862 (UniProt | EBI)

Last sequence update: 2005-03-15
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Secreted frizzled-related protein 2 {ECO:0000312|MGI:MGI:108078}; Short=sFRP-2;AltName: Full=Protein SDF5;AltName: Full=Secreted apoptosis-related protein 1; Short=SARP-1 {ECO:0000303|PubMed:9391078};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 295 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sfrp2	secreted frizzled-related protein 2	113	147	3	18

Sequence references in MGI

J:36732 Shirozu M, et al., Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics. 1996 Nov 1;37(3):273-80
J:39275 Rattner A, et al., A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2859-63
J:49904 Leimeister C, et al., Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech Dev. 1998 Jul;75(1-2):29-42
J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
J:164792 Melkonyan HS, et al., SARPs: a family of secreted apoptosis-related proteins. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13636-41
J:237943 Jia S, et al., Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Dev Biol. 2016 Dec 01;420(1):110-119