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Sequence Detail
ID/Version
P70218 Q99K62 Q8R3R0 (UniProt | EBI) Last sequence update: 1997-02-01
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 1; EC=2.7.11.1 {ECO:0000269|PubMed:11509653, ECO:0000269|PubMed:9003777};AltName: Full=Hematopoietic progenitor kinase; Short=HPK;AltName: Full=MAPK/ERK kinase kinase kina
Provider SWISS-PROT
Sequence
Polypeptide 827 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Map4k1 mitogen-activated protein kinase kinase kinase kinase 1 28 102 2 24
Sequence references in MGI J:37543 Kiefer F, et al., HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway. EMBO J. 1996 Dec 16;15(24):7013-25
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory