Sequence Detail

ID/Version

P62500 Q6PDK1 Q00992 Q9EQN4 Q69Z44 (UniProt | EBI)

Last sequence update: 2008-09-02
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=TSC22 domain family protein 1 {ECO:0000312|MGI:MGI:109127};AltName: Full=Regulatory protein TSC-22 {ECO:0000250|UniProtKB:P62501};AltName: Full=TGFB-stimulated clone 22 homolog {ECO:0000250|UniProtKB:P62501};AltName: Full=TSC22-related induc

Provider

SWISS-PROT

Sequence

Polypeptide 1077 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tsc22d1	TSC22 domain family, member 1	27	113	2	46

Sequence references in MGI

J:1170 Shibanuma M, et al., Isolation of a gene encoding a putative leucine zipper structure that is induced by transforming growth factor beta 1 and other growth factors. J Biol Chem. 1992 May 25;267(15):10219-24
J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:118536 Fiol DF, et al., Specific TSC22 domain transcripts are hypertonically induced and alternatively spliced to protect mouse kidney cells during osmotic stress. FEBS J. 2007 Jan;274(1):109-24
J:148897 Yu J, et al., TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. Blood. 2009 May 28;113(22):5558-67
J:169435 Huser CA, et al., TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival. Cell Death Differ. 2010 Feb;17(2):304-15
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:338157 Kato M, et al., Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-beta-induced collagen expression in kidney cells. J Biol Chem. 2010 Oct 29;285(44):34004-15