Sequence Detail

ID/Version

P60322 F8VQ09 (UniProt | EBI)

Last sequence update: 2011-12-14
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Nanos homolog 2; Short=NOS-2;

Provider

SWISS-PROT

Sequence

Polypeptide 136 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nanos2	nanos C2HC-type zinc finger 2	28	126	3	18

Sequence references in MGI

J:86522 Tsuda M, et al., Conserved role of nanos proteins in germ cell development. Science. 2003 Aug 29;301(5637):1239-41
J:117055 Suzuki A, et al., Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development. 2007 Jan;134(1):77-83
J:132711 Suzuki A, et al., Nanos2 suppresses meiosis and promotes male germ cell differentiation. Genes Dev. 2008 Feb 15;22(4):430-5
J:152220 Sada A, et al., The RNA-binding protein NANOS2 is required to maintain murine spermatogonial stem cells. Science. 2009 Sep 11;325(5946):1394-8
J:157579 Suzuki A, et al., NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9