Sequence Detail

ID/Version

P59266 Q5BKP7 B9EHX3 (UniProt | EBI)

Last sequence update: 2003-02-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Acyl-coenzyme A diphosphatase FITM2 {ECO:0000255|HAMAP-Rule:MF_03230}; EC=3.6.1.- {ECO:0000255|HAMAP-Rule:MF_03230};AltName: Full=Fat storage-inducing transmembrane protein 2 {ECO:0000255|HAMAP-Rule:MF_03230, ECO:0000303|PubMed:30923

Provider

SWISS-PROT

Sequence

Polypeptide 262 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fitm2	fat storage-inducing transmembrane protein 2	27	98	3	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:130956 Kadereit B, et al., Evolutionarily conserved gene family important for fat storage. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):94-9
J:230592 Choudhary V, et al., A conserved family of proteins facilitates nascent lipid droplet budding from the ER. J Cell Biol. 2015 Oct 26;211(2):261-71
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:297315 Gross DA, et al., Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19581-6
J:303195 Nishihama N, et al., Mice lacking fat storage-inducing transmembrane protein 2 show improved profiles upon pressure overload-induced heart failure. Heliyon. 2019 Mar;5(3):e01292