Sequence Detail

ID/Version

P58308 Q6VLX3 Q5SGC8 Q8BG12 (UniProt | EBI)

Last sequence update: 2003-05-30
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=Orexin receptor type 2; Short=Ox-2-R; Short=Ox2-R; Short=Ox2R;AltName: Full=Hypocretin receptor type 2;

Provider

SWISS-PROT

Sequence

Polypeptide 460 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hcrtr2	hypocretin (orexin) receptor 2	48	101	3	13

Sequence references in MGI

J:83817 Willie JT, et al., Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron. 2003 Jun 5;38(5):715-30
J:93583 Chen J, et al., Genomic organization of mouse orexin receptors: characterization of two novel tissue-specific splice variants. Mol Endocrinol. 2004 Nov;18(11):2790-804
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:312319 Xiao X, et al., Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun. 2021 Sep 2;12(1):5249