Sequence Detail

ID/Version

P56402 Q8VCG5 Q9R232 (UniProt | EBI)

Last sequence update: 2002-09-19
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Aquaporin-2; Short=AQP-2;AltName: Full=ADH water channel;AltName: Full=Aquaporin-CD; Short=AQP-CD;AltName: Full=Collecting duct water channel protein;AltName: Full=WCH-CD;AltName: Full=Water channel protein for renal collecti

Provider

SWISS-PROT

Sequence

Polypeptide 271 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aqp2	aquaporin 2	64	136	2	18

Sequence references in MGI

J:47478 Yang B, et al., cDNA and genomic cloning of mouse aquaporin-2: functional analysis of an orthologous mutant causing nephrogenic diabetes insipidus. Genomics. 1999 Apr 1;57(1):79-83
J:109463 McDill BW, et al., Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6952-7
J:110350 Gooch JL, et al., Loss of calcineurin Aalpha results in altered trafficking of AQP2 and in nephrogenic diabetes insipidus. J Cell Sci. 2006 Jun 15;119(Pt 12):2468-76
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89